Who we are

Frame Research provides rigorous summaries of medical evidence to health care decision makers. Our focus is on finding, evaluating, and assembling existing evidence – typically clinical studies published in peer-reviewed journals – in an objective manner.

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The founder of Frame Research and a resident of Brooklyn, NY, Diana Frame has 15 years of experience in evidence-based medicine research, primarily systematic literature review. She has advised decision makers at academic centers as well as pharmaceutical, biotechnology, and medical device clients. Areas of expertise include oncology, cardiology, outcomes benchmarking for phase 2/3 trials, and competitive landscape analysis. She has also led successful software development efforts for relational database, web, and mobile platforms, and has contributed to over 20 peer-reviewed publications and professional meeting abstracts. Diana received her master’s degree from Columbia University’s Mailman School of Public Health.

DFrame resume
DFrame publications

What we do

Each day, thousands of new articles are indexed in PubMed, the National Library of Medicine’s repository of journal citations. Planned and in-process studies in clinical medicine are increasingly searchable thanks to public registries, and these records too are continually updated. Patient-level Big Data in health care, such as electronic medical records and claims databases, has opened up still further avenues for retrospective research. It’s difficult just to keep up with this deluge of information, much less distill the messages relevant to specific clinical questions. Approaching all this data with a prospective, reproducible plan is what we do best. [See FRAMING A RESEARCH QUESTION on our Resources Page.]


Our PubSavvy Apps

At Frame Research, in addition to client projects, we’ve also tried to build some tools we hope will be useful for the community of health care researchers. Our iOS apps, PubSavvy PubMed Search and PubSavvy Swipe, interface with PubMed and allow you to search, browse, and save articles of interest. Check them out at



Frame Research keeps it lean and mean. We’ve been fortunate for the opportunity to collaborate with some of the fine folks you see here.