Here is a collection of tools and guidelines for systematic reviews and other EBM projects.


PubMed is the National Library of Medicine’s repository of citations and abstracts for biomedical journal articles. Over 26 million MEDLINE and publisher-supplied citations are searchable here.

Registry of ongoing clinical trials – important information as it reflects planned trials, and can be used to help assess publication bias (the tendency for successful studies to be more widely disseminated than failed or non-significant studies).

Cochrane Collaboration

Well-respected systematic reviews, produced by an academic consortium. An exhaustive guide to conducting high-quality systematic reviews is provided in their online Handbook. Completed reviews can be searched at (most require a subscription to read in full text).


Guideline on reporting systematic reviews and meta-analyses. If you want to publish your literature review in a peer-reviewed journal, make sure to follow this checklist.

Oxford CEBM

Centre for Evidence-based Medicine in the UK – originators of a widely-used hierarchy of evidence.


US Agency for Health Care Research & Quality – commissions comparative effectiveness research meant to give patients and providers more information about the risks and benefits of different treatments.


Search US regulatory documents for pharmaceutical products – look up by brand or generic name, or browse by date. Supplementary Basis of Approval documents sometimes contain detail not available in published studies.

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