Welcome to Frame Research
Helping you frame your research questions since 2006
Frame Research, LLC provides rigorous summaries of medical evidence to health care decision makers. Our focus is on finding, evaluating, and assembling existing evidence – typically clinical studies published in peer-reviewed journals – in an objective manner.
Services
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Systematic Review
Frame Research follows current best practices for systematic literature review, using prospectively-defined search strategies and study selection criteria. We apply our experience and rigor to produce data sets suitable for use in meta-analyses and peer-reviewed publications.
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Therapeutic Landscape
We apply a streamlined literature review process to gather evidence on broad disease settings or to characterize a landscape of available therapies. Our clients use the resulting evidence base for competitive intelligence assessments, clinical context for manuscripts, and post-marketing surveillance.
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Rapid Review
Searching the medical literature for studies that have already been conducted is a key step in evidence generation, even if a full systematic review is not in the cards. When a timely answer to a targeted question is needed, we help you round up the relevant evidence and summarize findings in an actionable format.
Who We Are
The founder of Frame Research and a resident of Brooklyn, NY, Diana Frame has 20 years of experience in evidence-based medicine research. Diana has advised companies in the pharmaceutical, biotechnology, and medical device industries as well as academic and non-profit organizations. Her analytic work, primarily based on systematic review of published literature, informs clinical trials planning, burden of illness and competitive landscape assessments, regulatory and payer strategy, and economic models. Clinical areas of expertise include oncology, medical devices, and cardiovascular disease. She has also led successful software development efforts for relational database, web, and mobile platforms, and has contributed to two dozen peer-reviewed publications. Diana received her undergraduate degree from Washington University in St. Louis and holds a Master's degree in Public Health from Columbia University's Mailman School.